Turbochargers are a consumable item. Every turbo will eventually wear out and fail. Turbo's on diesel trucks can last a million miles primarily due to the lower exhaust temperatures of diesels compared to gasoline engines, but they can fail if abused too. Despite water cooling, and whatever a manufacturer may say, abusing a turbo, by not idling the engine before shutting it down, (with a longer idle time if coming in after a hot highway run ie.) can contribute to a turbo failing earlier than it otherwise might.
Cant cant count how many times I've seen owners of turbocharged vehicles, come screaming into a parking place and immediately shut the motor down. Not something I would do, but not my vehicle. Routinely "barking" a turbo, just getting into significant boost and totally letting off of the throttle is also not conducive to turbo longevity. There are ways to minimize that with pressure relief systems (the pop off valve on our modified Subaru in the signature is one), but I'm not sure what Ford has done in that regard on their turbo vehicles. A waste gate, which all turbo'd vehicles have, only activates when pre-programmed boost levels are exceeded and doesn't come into play in a "barking" scenario.
I've read about Eco boost F150's accumulating over 100K miles with no turbo issues, but if I were to own one and intended to keep it for the long term, replacing the turbo's at some point would have to be a consideration. Also making sure my OCI's don't exceed 5K miles is another on the Eco boost. The DI engine tends to fuel saturate the oil. Also, those motors can experience significant timing chain wear if OCI's are extended.
Not bashing the Eco boost at all, just some considerations. Our 5.7 hemi is not without those. All the reports of valve train tick and failing lifters wearing cam lobes are just two that come to mind.
Good luck with your new truck.